Author’s response to reviews Title: Central nervous system Gadolinium accumulation in patients undergoing periodical contrast MRI screening for hereditary tumor syndromes Authors: Evelynn Vergauwen ([email protected])

نویسندگان

  • Anne-Marie Vanbinst
  • Carola Brussaard
  • Peter Janssens
  • Dieter De Clerck
  • Anne Cees Houtman
  • Susanne Bohler
چکیده

Title: Central nervous system Gadolinium accumulation in patients undergoing periodical contrast MRI screening for hereditary tumor syndromes Authors: Evelynn Vergauwen ([email protected]) Anne-Marie Vanbinst ([email protected]) Carola Brussaard ([email protected]) Peter Janssens ([email protected]) Dieter De Clerck ([email protected]) Michel Van Lint ([email protected]) Anne Cees Houtman ([email protected]) Olaf Michel ([email protected]) Kathelijn Keymolen ([email protected]) Bieke Lefevere ([email protected]) Susanne Bohler ([email protected]) Dirk Michielsen ([email protected]) Anna Jansen ([email protected]) Vera Van Velthoven ([email protected]) Sven Gläsker ([email protected]) Version: 1 Date: 06 Dec 2017 Author’s response to reviews: Dear Professor Lubinski and Professor Scott,

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Central nervous system gadolinium accumulation in patients undergoing periodical contrast MRI screening for hereditary tumor syndromes

Background Patients with hereditary tumor syndromes undergo periodical magnetic resonance imaging (MRI) screening with Gadolinium contrast. Gadolinium accumulation has recently been described in the central nervous system after repeated administrations. The prevalence and rate of accumulation in different subgroups of patients are unknown. Neither are the mechanism nor clinical impact. This may...

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تاریخ انتشار 2017